March Madness 2025 bracket: NCAA Tournament picks, predictions from advanced college basketball model

The 2025 NCAA Tournament bracket was unveiled on Selection Sunday, with 14 of the 16 SEC teams landing a spot in the 2025 March Madness bracket. The Auburn Tigers and Florida Gators each earned No. 1 seeds, while the Tennessee Volunteers and Alabama Crimson Tide landed No. 2 seeds. Auburn is the top overall seed in the 2025 NCAA basketball bracket and will try to win the program’s first ever college basketball national championship. The Tigers have made one Final Four appearance in 2019, when they lost to eventual national champion Virginia.

The Tigers are led by veteran coach Bruce Pearl and will play the winner of the Alabama State vs. St. Francis (PA) First Four game. Does Auburn have the makings of a legitimate national title-contender? Should you instead target one of the potential 2025 March Madness sleepers in the South Region? Before filling out your NCAA Tournament bracket 2025, be sure to see the 2025 March Madness bracket picks from the proven computer model at SportsLine.

SportsLine’s proven projection model has simulated every game in the tournament 10,000 times. It has absolutely crushed its March Madness picks recently, beating over 91% of all CBS Sports brackets in four of the past six tournaments. It was all over UConn’s championship run a year ago and nailed 13 teams in the Sweet 16. It also nailed Alabama’s Cinderella run to the Final Four as a 4-seed.

It knows how to spot an upset as well. The same model has produced brackets that have nailed 24 first-round upsets by double-digit seeds since its inception in 2016.

There’s no reason to rely on luck when there’s proven technology to help you dominate your 2025 March Madness picks. Now, with the 2025 NCAA bracket revealed, the model is simulating the matchups and its results are in. You can only see it over at SportsLine.

Top 2025 March Madness bracket picks

One of the Midwest Region picks from the model: No. 2 seed Tennessee, despite losing to Kentucky twice this season, beats Kentucky in the Sweet 16. The Vols enter the tournament with an elite defense for the fifth year in a row under veteran head coach Rick Barnes. They lost SEC Player of the Year Dalton Knecht from last year’s Elite Eight team, but they added a trio of impressive transfers in Chaz Lanier, Igor Milicic Jr. and Felix Okpara.

Senior point guard Zakai Zeigler is Tennessee’s all-time assists leader, averaging 13.1 points and 7.5 assists per game. Kentucky is without guard Jaxson Robinson due to a season-ending wrist injury, and guard Lamont Butler has been dealing with a lingering shoulder injury. The Wildcats are not nearly as good as Tennessee defensively, which is one reason why the model has the Vols avenging their regular-season losses.

Another surprise: No. 5 Clemson takes down No. 4 Purdue in the second round of the Midwest. The Tigers won a program record 27 games during the regular season before falling to Louisville in the ACC Tournament semifinals. Clemson takes on the McNeese Cowboys in the first round of the NCAA Tournament on Thursday, and are projected to match up with Purdue in the second round on Saturday.

Clemson enters March Madness 2025 with a NET ranking of 22 in the country, and is 2-1 against top-25 teams this season. The Tigers shoot the ball well, and have a balanced attack with four players averaging 11.3 points or more per game. Senior guard Chase Hunter leads the way, averaging 16.4 points, 3.0 rebounds, and 2.5 assists per game. You can see the model’s 2025 NCAA bracket picks here.

How to make 2025 NCAA bracket predictions

Who wins every tournament-defining matchup, and which teams will make surprising runs through the 2025 NCAA Tournament bracket? With the model’s track record of calling bracket-busting upsets, you’ll want to see which stunners it’s calling this year before locking in any 2025 NCAA bracket picks.

So what’s the optimal NCAA Tournament 2025 bracket, and which NCAA Tournament Cinderella teams will shock college basketball? Visit SportsLine now to see which region features three must-have upsets, including a play-in team that absolutely stuns its first-round opponent, all from the model that’s beaten 91% of bracket players in four of the last six tournaments.



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