Astros vs. Royals Prediction, Odds, Picks – April 27

Data Skrive

Jeremy Pena and the Houston Astros will attempt to take down Maikel Garcia and the Kansas City Royals when the teams meet on Sunday at 2:10 p.m. ET. The Astros have been listed as -132 moneyline favorites for this matchup against the Royals (+113). Houston is the favorite on the run line (-1.5 with +137 odds). The total for the game is set at 7.5 runs.

Here is everything you need to know from a betting perspective on the Astros-Royals game, regarding the run line, moneyline and total, plus expert picks.

Keep up with MLB on FOX Sports.

Astros vs. Royals Game Information & Odds

• When: Sunday, April 27, 2025 at 2:10 p.m. ET
• Where: Kauffman Stadium in Kansas City, Missouri
• How to watch on TV: FDSKC and SCHN

Astros vs. Royals Prediction

• Score Prediction: Astros 4, Royals 3
• Total Prediction: Under 7.5 runs
• Win Probabilities: Astros 50%, Royals 50%

Astros vs. Royals Betting Insights

• This season, the Astros have won eight out of the 16 games, or 50%, in which they’ve been favored.
• Houston has a record of 5-3 when favored by -132 or more by sportsbooks this season.
• The implied probability of a win from the Astros, based on the moneyline, is 56.9%.
• The Royals have come away with four wins in the 14 contests they have been listed as the underdogs in this season.
• This year, Kansas City has won one of seven games when listed as at least +113 or worse on the moneyline.
• The moneyline set for this matchup implies the Royals have a 46.9% chance of coming away with a victory in the contest.

Houston Astros

HOU

-1.5

-134

O 7.5

Kansas City Royals

KC

+1.5

+114

U 7.5

Check out the best highlights between the Los Angeles Angels and the Houston Astros.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

Want great stories delivered right to your inbox? Create or log in to your FOX Sports account, follow leagues, teams and players to receive a personalized newsletter daily.

FOLLOW Follow your favorites to personalize your FOX Sports experience

Kansas City Royals

Houston Astros